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Search Results for " Mammalian target of Rapamycin "

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カタログ番号	製品名	別名	ターゲット
T14033	3BDO		Apoptosis , mTOR , Autophagy
	3BDO is an activator of mTOR. It can also inhibit autophagy..		Apoptosis , mTOR , Autophagy
T40351	MHY-1685		mTOR
	MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can rejuvenate senile hCSCs by modulating autophagy.		mTOR
T6030	XL388		P450 , PI3K , mTOR
	XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.		P450 , PI3K , mTOR
T6045	Torin 1		DNA-PK , PI3K , mTOR , Autophagy
	Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.		DNA-PK , PI3K , mTOR , Autophagy
T5472	PQR620		mTOR
	PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.		mTOR
T2475	KU-0063794		mTOR
	KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.		mTOR
T3514	CZ415		mTOR
	CZ415 is a potent and highly selective mTOR inhibitor.		mTOR
T1859	AZD-8055		Apoptosis , mTOR , Autophagy
	AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.		Apoptosis , mTOR , Autophagy
T12270	NV-5138		mTOR
	NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.		mTOR
T12123	MTOR inhibitor-3		mTOR
			mTOR
T5338	MTOR inhibitor-1		mTOR , Autophagy
	C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.		mTOR , Autophagy
T6100	Torin 2		Apoptosis , ATM/ATR , DNA-PK , mTOR , Autophagy
	Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 2...		Apoptosis , ATM/ATR , DNA-PK , mTOR , Autophagy
T16355	NSC781406		PI3K , mTOR
	NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).		PI3K , mTOR
T7166	GNE-493		PI3K , mTOR
	GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR,respectively.		PI3K , mTOR
T7343	PF-04979064		PI3K , mTOR
	PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).		PI3K , mTOR
T6845	GNE-317	GNE317	PI3K , mTOR
	GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).		PI3K , mTOR
T1961	Vistusertib	AZD2014	Apoptosis , Akt , PI3K , S6 Kinase , mTOR , Autophagy
	Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.		Apoptosis , Akt , PI3K , S6 Kinase , mTOR , Autophagy
T16567	PQR530	PQR-530	PI3K , mTOR
	PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitu...		PI3K , mTOR
T3692	GNE-477	GNE 477	PI3K , mTOR
	GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.		PI3K , mTOR
T1908	MHY1485		mTOR , Autophagy
	MHY1485 is a mTOR activator. It inhibits the autophagic process by inhibition of fusion between autophagosomes and lysosomes, leading to the accumulation of LC3II protein and enlarged autophagosomes.		mTOR , Autophagy
T36083	DS-7423		PI3K , mTOR
	DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. DS-7423 increases TP53 expression, the level of p-TP53 on Ser...		PI3K , mTOR
T3541	CC-115	CC 115	DNA-PK , PI3K , mTOR
	CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).		DNA-PK , PI3K , mTOR
T22339	GNE-490		Others , PI3K
	GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM).		Others , PI3K
T2084	ETP-46464		ATM/ATR , DNA-PK , PI3K , mTOR
	ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).		ATM/ATR , DNA-PK , PI3K , mTOR
T2357	GSK1059615	GSK 1059615,GSK-1059615	Apoptosis , PI3K , mTOR
	GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.		Apoptosis , PI3K , mTOR
T2414	Torkinib	PP 242	Apoptosis , Mitophagy , PI3K , mTOR , Autophagy
	Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).		Apoptosis , Mitophagy , PI3K , mTOR , Autophagy
T6251	PF-04691502	PF4691502	Akt , PI3K , mTOR , Autophagy
	PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.		Akt , PI3K , mTOR , Autophagy
T6510	GDC-0349	RG-7603	PI3K , mTOR , Autophagy
	GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.		PI3K , mTOR , Autophagy
T6557	KU-0060648	KU0060648	DNA-PK , PI3K , mTOR
	KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.		DNA-PK , PI3K , mTOR
T4199	Desmethyl-VS-5584		PI3K , mTOR
	Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.		PI3K , mTOR
T6319	OSI-027	ASP4786,OSI027	DNA-PK , PI3K , mTOR , Autophagy
	OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. Phase 1.		DNA-PK , PI3K , mTOR , Autophagy
T25399	ETP-45658	ETP45658,ETP 45658	DNA-PK , PI3K , mTOR
	ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively...		DNA-PK , PI3K , mTOR
T6143	PI-103	PI103,PI 103	Apoptosis , DNA-PK , PI3K , mTOR , Autophagy
	PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).		Apoptosis , DNA-PK , PI3K , mTOR , Autophagy
T3351	Onatasertib	CC223,CC 223,CC-223	Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
	Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity. Onatasertib inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor ce...		Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
T12459	PI3K/mTOR Inhibitor-2		PI3K , mTOR
			PI3K , mTOR
T2415	PP121		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
	PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).		Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
T6103	VS-5584	SB2343,VS 5584,VS5584	PI3K , mTOR
	VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.		PI3K , mTOR
T6346	WYE-132	WYE 125132,WYE125132,WYE-125132	Apoptosis , mTOR
	WYE-125132 (WYE-132 (WYE-125132)) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.		Apoptosis , mTOR
T7014	Voxtalisib	XL765,SAR245409	DNA-PK , PI3K , mTOR
	Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.		DNA-PK , PI3K , mTOR
T6883	Samotolisib	GTPL8918,LY3023414	DNA-PK , PI3K , mTOR , Autophagy
	Samotolisib (LY3023414) is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. Samotolisib (LY3023414) has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, ...		DNA-PK , PI3K , mTOR , Autophagy
T6334	Ridaforolimus	AP23573,Deforolimus,MK-8669	mTOR , Autophagy
	Ridaforolimus (AP23573) is a small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamyc...		mTOR , Autophagy
T2706	Palomid 529	P529,SG 00529	Apoptosis , mTOR
	Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.		Apoptosis , mTOR
T1784	Everolimus	RAD001,SDZ-RAD	Apoptosis , Others , mTOR , Autophagy
	Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.		Apoptosis , Others , mTOR , Autophagy
T1861	Omipalisib	GSK458,GSK2126458	PI3K , mTOR , Autophagy
	Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.		PI3K , mTOR , Autophagy
T16156	MT 63-78		Apoptosis , AMPK , mTOR
	MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cel...		Apoptosis , AMPK , mTOR
T1970	Gedatolisib	PF-05212384,PKI-587	PI3K , mTOR
	Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signaling pathway.		PI3K , mTOR
T2145	Temsirolimus	NSC 683864,CCI-779	Apoptosis , mTOR , Autophagy
	Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.		Apoptosis , mTOR , Autophagy
T9831	MKC-1	Ro-31-7453	Apoptosis , Akt , Microtubule Associated , mTOR
	MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format...		Apoptosis , Akt , Microtubule Associated , mTOR
T6072L	BGT226	BGT226 free base,NVP-BGT226	PI3K , mTOR , Autophagy
	BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.		PI3K , mTOR , Autophagy
T6730	WAY-600	WAY600	VEGFR , PI3K , Src , mTOR
	WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold...		VEGFR , PI3K , Src , mTOR

Compounds

3BDO

T14033

Synonym:

Target: Apoptosis, mTOR, Autophagy

Target: P450, PI3K, mTOR

Torin 1

T6045

Synonym:

Target: DNA-PK, PI3K, mTOR, Autophagy

Target: Apoptosis, mTOR, Autophagy

Target: mTOR, Autophagy

Torin 2

T6100

Synonym:

Target: Apoptosis, ATM/ATR, DNA-PK, mTOR, Autophagy

Target: Apoptosis, Akt, PI3K, S6 Kinase, mTOR, Autophagy

Target: mTOR, Autophagy

Target: DNA-PK, PI3K, mTOR

Target: ATM/ATR, DNA-PK, PI3K, mTOR

GSK1059615

T2357

Synonym: GSK 1059615,GSK-1059615

Target: Apoptosis, PI3K, mTOR

Torkinib

T2414

Synonym: PP 242

Target: Apoptosis, Mitophagy, PI3K, mTOR, Autophagy

PF-04691502

T6251

Synonym: PF4691502

Target: Akt, PI3K, mTOR, Autophagy

GDC-0349

T6510

Synonym: RG-7603

Target: PI3K, mTOR, Autophagy

KU-0060648

T6557

Synonym: KU0060648

Target: DNA-PK, PI3K, mTOR

Synonym: ASP4786,OSI027

Target: DNA-PK, PI3K, mTOR, Autophagy

ETP-45658

T25399

Synonym: ETP45658,ETP 45658

Target: DNA-PK, PI3K, mTOR

PI-103

T6143

Synonym: PI103,PI 103

Target: Apoptosis, DNA-PK, PI3K, mTOR, Autophagy

Onatasertib

T3351

Synonym: CC223,CC 223,CC-223

Target: Apoptosis, c-Fms, DNA-PK, FLT, PI3K, mTOR

PI3K/mTOR Inhibitor-2

Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck

VS-5584

T6103

Synonym: SB2343,VS 5584,VS5584

Target: PI3K, mTOR

WYE-132

T6346

Synonym: WYE 125132,WYE125132,WYE-125132

Target: Apoptosis, mTOR

Voxtalisib

T7014

Synonym: XL765,SAR245409

Target: DNA-PK, PI3K, mTOR

Samotolisib

T6883

Synonym: GTPL8918,LY3023414

Target: DNA-PK, PI3K, mTOR, Autophagy

Ridaforolimus

T6334

Synonym: AP23573,Deforolimus,MK-8669

Target: mTOR, Autophagy

Palomid 529

T2706

Synonym: P529,SG 00529

Target: Apoptosis, mTOR

Everolimus

T1784

Synonym: RAD001,SDZ-RAD

Target: Apoptosis, Others, mTOR, Autophagy

Omipalisib

T1861

Synonym: GSK458,GSK2126458

Target: PI3K, mTOR, Autophagy

MT 63-78

T16156

Synonym:

Target: Apoptosis, AMPK, mTOR

Gedatolisib

T1970

Synonym: PF-05212384,PKI-587

Target: PI3K, mTOR

Temsirolimus

T2145

Synonym: NSC 683864,CCI-779

Target: Apoptosis, mTOR, Autophagy

MKC-1

T9831

Synonym: Ro-31-7453

Target: Apoptosis, Akt, Microtubule Associated, mTOR

BGT226

T6072L

Synonym: BGT226 free base,NVP-BGT226

Target: PI3K, mTOR, Autophagy

WAY-600

T6730

Synonym: WAY600

Target: VEGFR, PI3K, Src, mTOR

カタログ番号	製品名	別名	ターゲット
T2717	Salidroside	Rhodioloside	Apoptosis , mTOR
	Salidroside (Rhodioloside) is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.		Apoptosis , mTOR
T2998	Dihydromyricetin	Ampelopsin,Ampeloptin	Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy
	Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy...
T3O2749	L-Leucine	(S)-Leucine,Leu	mTOR
	L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar lev...		mTOR
T5S0506	Rotundic acid	Rutundic acid	Apoptosis , Others , p38 MAPK , Akt , mTOR
	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...		Apoptosis , Others , p38 MAPK , Akt , mTOR
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T6354	(+)-Usnic acid	D-Usnic Acid,(+)-Usniacin	Antiviral , Antibacterial , mTOR
	(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.		Antiviral , Antibacterial , mTOR
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T1537	Rapamycin	Sirolimus,AY 22989,NSC-2260804	Others , Endogenous Metabolite , Antibiotic , mTOR , Autophagy , Antifungal
	Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy.
T2974	Cyclovirobuxine D	CVB-D,Bebuxine,Cyclovirobuxin D	Apoptosis , Others , Akt , mTOR , Autophagy
	Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.		Apoptosis , Others , Akt , mTOR , Autophagy
T5740	25(R,S)-Ruscogenin	(25RS)-Ruscogenin	Others , HIF
	25(R,S)-Ruscogenin is a natual product.		Others , HIF
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy

天然物製品

Salidroside

T2717

Synonym: Rhodioloside

Target: Apoptosis, mTOR

Dihydromyricetin

T2998

Synonym: Ampelopsin,Ampeloptin

Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy

L-Leucine

T3O2749

Synonym: (S)-Leucine,Leu

Target: mTOR

Rotundic acid

T5S0506

Synonym: Rutundic acid

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

(+)-Usnic acid

T6354

Synonym: D-Usnic Acid,(+)-Usniacin

Target: Antiviral, Antibacterial, mTOR

Arnicolide D

TN1405

Synonym:

Target: Akt, Caspase, PI3K, STAT, mTOR

Rapamycin

T1537

Synonym: Sirolimus,AY 22989,NSC-2260804

Target: Others, Endogenous Metabolite, Antibiotic, mTOR, Autophagy, Antifungal

Cyclovirobuxine D

T2974

Synonym: CVB-D,Bebuxine,Cyclovirobuxin D

Target: Apoptosis, Others, Akt, mTOR, Autophagy

25(R,S)-Ruscogenin

T5740

Synonym: (25RS)-Ruscogenin

Target: Others, HIF

Hederacolchiside A1

T2P2806

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02200	TXNIP Protein, Human, Recombinant (B2M & His)	Human	in vitro E. coli expression system
	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated ...
TMPH-02929	TXNIP Protein, Mouse, Recombinant (His)	Mouse	Yeast
	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated ...
TMPY-04540	S6K1/RPS6KB1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase...

TXNIP Protein, Human, Recombinant (B2M & His)

TMPH-02200

Species: Human

Expression System: in vitro E. coli expression system

TXNIP Protein, Mouse, Recombinant (His)

TMPH-02929

Species: Mouse

Expression System: Yeast

S6K1/RPS6KB1 Protein, Human, Recombinant (GST)

TMPY-04540

Species: Human

Expression System: Baculovirus-Insect Cells

カタログ番号	製品名
L1300	PI3K-AKT-mTOR Compound Library		425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;

ライブラリー

PI3K-AKT-mTOR Compound Library

L1300

Compounds: 425